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Efficacy + moisturization for adults with plaque psoriasis

Dry, Thick Plaques


ULTRAVATE® Lotion’s hydrating formulation enhances steroid absorption and moisturizes dry, thick plaques.1-4

Male with plaque psoriasis on his knee, treated with ULTRAVATE® Lotion (halobetasol propionate, 0.05%) twice daily for 14 days.*
*Individual patient results. Actual results may vary.
Baseline
Day 14
2 Week Results
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Large Body Surface Areas


ULTRAVATE® Lotion offers the elegance and spreadability of a lotion, while providing the hydrating benefits of a cream.2,3

Male with plaque psoriasis on his back, treated with ULTRAVATE® Lotion (halobetasol propionate, 0.05%) twice daily for 14 days.*
*Individual patient results. Actual results may vary.
Baseline
Day 14
2 Week Results
See the 2-week difference

Elbows & Knees


Formulated with hydrating emollients to increase and maintain skin moisturization.1,2

Male with plaque psoriasis on his elbow, treated with ULTRAVATE® Lotion (halobetasol propionate, 0.05%) twice daily for 14 days.*
*Individual patient results. Actual results may vary.
Baseline
Day 14
2 Week Results

Male with plaque psoriasis on his knee, treated with ULTRAVATE® Lotion (halobetasol propionate, 0.05%) twice daily for 14 days.*
*Individual patient results. Actual results may vary.

Baseline
Day 14
2 Week Results
References: 1. ULTRAVATE® Lotion [prescribing information]. Cranbury, NJ: Sun Pharmaceutical Industries, Inc.; 2017. 2. Grove G, Zerweck C, Houser T, et al. Occlusivity and moisturization potential of a new lotion formulation of halobetasol propionate, 0.05%. Poster presented at: 74th Annual Meeting of the American Academy of Dermatology; March 4-8, 2016; Washington, DC. 3. Pariser D, Bukhalo M, Guenthner S, et al. Two multicenter, randomized, double-blind, parallel group comparison studies of a novel enhanced lotion formulation of halobetasol propionate lotion, 0.05% versus its vehicle lotion in adult subjects with plaque psoriasis. J Drugs Dermatol. 2017;16(3):234-240. 4. Feldman SR. Relative efficacy and interchangeability of various clobetasol propionate vehicles in the management of steroid-responsive dermatoses. Curr Ther Res Clin Exp. 2005;66(3):154-171.
INDICATIONS AND USAGE

ULTRAVATE (halobetasol propionate) Lotion is a corticosteroid indicated for the topical treatment of plaque psoriasis in patients 18 years of age and older.

IMPORTANT SAFETY INFORMATION

Effects on Endocrine System: Reversible hypothalamic-pituitary-adrenal (HPA) axis suppression may occur, with the potential for glucocorticosteroid insufficiency during or after treatment. Systemic effects of topical corticosteroids may also include Cushing’s syndrome, hyperglycemia, and glucosuria. Systemic absorption may require evaluation for HPA axis suppression. Use of potent corticosteroids on large areas, for prolonged durations, under occlusive dressings, or on an altered skin barrier may increase systemic exposure. Children may be more susceptible to systemic toxicity when treated with topical steroids.

Local Adverse Reactions: Local adverse reactions with topical steroids may include atrophy, striae, telangiectasias, burning, itching, irritation, dryness, folliculitis, acneiform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, secondary infection and miliaria. These may be more likely to occur with occlusive use, prolonged use or more potent corticosteroids, including ULTRAVATE.

Concomitant Skin Infections: Use an appropriate antimicrobial agent if a skin infection is present or develops.

Allergic Contact Dermatitis: Discontinue ULTRAVATE Lotion if allergic contact dermatitis is established.
In clinical trials the most common adverse reactions (≥1%) were telangiectasia, application site atrophy, and headache.

Please see the Full Prescribing Information for complete prescribing details.